Thyronorm Tablets (Generic Synthroid) – Product Information
Thyronorm Tablets (Generic Synthroid) containing the active ingredient Levothyroxine sodium / Thyroxine sodium is used to treat Hypothyroidism as replacement or supplemental therapy in congenital or acquired hypothyroidism. It is also used in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis (Hashimoto’s thyroiditis)and multinodular goiter.
Thyronorm tablets can be used during pregnancy without any risk to the developing fetus. Thyronorm tablets are manufactured by Abbott India Limited in the strengths of 12.5 mcg, 25 mcg, 50 mcg, 62.5 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg and 150 mcg. We also have in stock Eltroxin Tablets which is used as a hormone replacement for individuals with hypothyroidism and to treat goiter.
Name of the Drug
We supply original Thyronorm tablets manufactured by Abbott India Limited.
Manufacturer of Thyronorm Tablets
Abbott India Limited
Active Ingredient present in Thyronorm Tablets
The active ingredient present in Thyronorm Tablets is Levothyroxine Sodium / Thyroxine sodium. Each Thyronorm tablet contains 12.5 mcg, 25 mcg, 50 mcg, 62.5 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg or 150 mcg of Levothyroxine Sodium.
Uses of Generic Synthroid (Thyronorm by Abbott)
Thyronorm by Abbott treats patients suffering from low thyroid hormone levels (hypothyroidism). Levothyroxine Sodium is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by a hormone imbalances, or from radiation treatment, or surgery, or cancer. Do not use Levothyroxine Sodium to treat obesity or weight problems.
Levothyroxine Sodium is a replacement for a hormone that is normally produced by your thyroid gland. This hormone regulates the body’s energy levels and importantly the metabolism. Levothyroxine Sodium is given when the thyroid gland seize to produce enough of the hormone on its own.
We supply Thyronorm by Abbott which is also known as Generic Synthroid. The active ingredient is Levothyroxine Sodium.
This is an original product by Abbott India Limited.
Thyronorm (Levothyroxine Sodium Tablets) – Dosage
Thyronorm should be taken in the morning on an empty stomach, at least one-half hour before any food is eaten. Levothyroxine Sodium tablets should be taken at least 4 hours apart from drugs that are known to interfere with its absorption. Due to the long half-life of Levothyroxine, the peak medical effect at a given dose of Levothyroxine Sodium may not be reached for 4 to 6 weeks after starting treatment.
Hypothyroidism in Adults and in Children in Whom Growth and Puberty are Complete:
Treatment may start at full replacement doses in otherwise healthy individuals less than 50 years old and in those older than 50 years who have been recently treated for hyperthyroidism or who have been hypothyroid for only a short time (such as a few months). The average full replacement dose of Levothyroxine Sodium tablets is approximately 1.7 mcg/kg/day (e.g., 100—125 mcg/day for a 70 kg adult). Older patients may require less than 1 mcg/kg/day. Thyronorm doses greater than 200 mcg/day are seldom required.
How to Use Thyronorm (Levothyroxine Sodium Tablets)
Take Thyronorm by Abbott (Levothyroxine Sodium tablets) exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Your doctor may occasionally change your dose to make sure you get the best results from this medication.
It is very important to take your Thyronorm tablet with a full glass (8 ounces) of water. The tablet can dissolve very quickly and swell in the throat, possibly causing choking or gagging. Take this medicine on an empty stomach, 30 minutes before eating.
Thyronorm by Abbott (Generic Synthroid) is usually taken in the morning. Follow your doctor’s dosing instructions and try to take this medication at the same time each day.
It may take several weeks before your body starts to respond to this medicine. Do not stop taking this medication suddenly. Even if you feel well, you may still need to take this medicine every day for the rest of your life to replace the thyroid hormone your body cannot produce.
To be sure this medicine is helping your condition; your blood will need to be tested often. Your liver or kidney function may also need to be tested. Visit your doctor regularly.
Tell any doctor or dentist who treats you that you are using this medicine.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose
Thyronorm Side effects
The side effects of Thyronorm (Levothyroxine Sodium tablets) are given below. They are mainly due to hyperthyroidism due to therapeutic overdosage. The Thyronorm side effects include the following:
- General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating;
- Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia;
- Musculoskeletal: tremors, muscle weakness;
- Cardiac: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest;
- Pulmonary: dyspnea;
- GI: diarrhea, vomiting, abdominal cramps;
- Dermatologic: hair loss, flushing;
- Reproductive: menstrual irregularities, impaired fertility.
Get emergency medical help if you have any signs of an allergic reaction including hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
• sleep problems (insomnia)
• nervous or irritable feeling
• fever, hot flashes, sweating
• changes in your menstrual periods
• appetite changes, weight changes
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about Levothyroxine Sodium side effects.
Levothyroxine Sodium Overdosage
The signs and symptoms of Thyronorm overdosage are those of hyperthyroidism and in some cases confusion and disorientation can occur. Cerebral embolism, shock, coma, and death have been reported. Seizures have occurred in a child ingesting approximately 20 mg of Levothyroxine Sodium (Thyronorm tablets) . Symptoms may not necessarily be evident or may not appear until several days after taking Levothyroxine Sodium tablets.
Treatment of Overdosage:
Levothyroxine sodium should be reduced in dose or temporarily discontinued if signs or symptoms of overdosage occur. Acute Massive Overdosage – This can be a life-threatening emergency, hence, symptomatic and supportive therapy should be started immediately. If not contraindicated (e.g., by seizures, coma, or loss of the gag reflex), the stomach should be emptied by emesis or gastric lavage to reduce gastrointestinal absorption. Activated charcoal or cholestyramine can also be used to decrease absorption. Central and peripheral increased sympathetic activity may be treated by administering B-receptor antagonists, e.g., propranolol (1 to 3 mg intravenously over a 10-minute period, or orally, 80 to 160 mg/day). Provide respiratory support as required and control congestive heart failure. Fever, hypoglycemia, and fluid loss should be controlled as necessary. Glucocorticoids may be given to prevent the conversion of T4 to T3.
Thyronorm Tablets (Generic Synthroid) Contraindications
Thyronorm Tablets (Generic Synthroid) are contraindicated in patients with a hypersensitivity to Levothyroxine sodium or to any of the inactive ingredients in Thyronorm tablets.
Levothyroxine Sodium is also contraindicated in patients with untreated subclinical (suppressed serum TSH level with normal T3 and T4 levels) or overt thyrotoxicosis of any etiology as well as in patients with acute myocardial infarction. Thyronorm (Levothyroxine Sodium Tablets) is contraindicated in patients with uncorrected adrenal insufficiency since thyroid hormones can precipitate an acute adrenal crisis by increasing the metabolic clearance of glucocorticoids.
Warnings & Precautions When Using Thyronorm Tablets (Generic Synthroid)
Since thyroid hormone occurs naturally in the body, almost anyone can take Generic Synthroid (Levothyroxine Sodium). You should not use Thyronorm by Abbott (Generic Synthroid) if you have had a heart attack, a thyroid disorder called thyrotoxicosis, or an adrenal gland problem that is not controlled by treatment.
Before taking Thyronorm by Abbott, tell your doctor if you have heart disease, coronary artery disease, anemia (lack of red blood cells), diabetes, problems with your pituitary or adrenal glands, or a history of blood clots.
If you use insulin or take diabetes medicine by mouth, ask your doctor if your dose needs to be changed when you start using this medicine.
It is safe to use while you are pregnant. It is also safe to use while you are breast-feeding a baby. This drug does pass into breast milk but it is not expected to be harmful to a nursing infant.
Tell your doctor if you become pregnant during treatment. You may need to increase your dose during pregnancy or if you plan to breast-feed.
In most cases, you will need to take Thyronorm (Generic Synthroid) for the rest of your life. Taking Thyronorm by Abbott (Levothyroxine Sodium) over long periods of time may cause bone loss, which can lead to osteoporosis. Talk with your doctor about how this could affect you.
Avoid the following food products, which can make your body absorb less of this medicine: infant soy formula, cotton seed meal, walnuts, and high-fiber foods.
Levothyroxine Sodium During Pregnancy
Levothyroxine Sodium has been classified by the US FDA as Pregnancy Category A. Studies in pregnant women treated with oral Levothyroxine Sodium (Thyronorm tablets) to maintain a euthyroid state have not shown an increased risk of fetal abnormalities.
Hypothyroidism during pregnancy is associated with a greater risk of complications, including spontaneous abortion, preeclampsia, stillbirth and premature delivery. Maternal hypothyroidism can have an adverse effect on fetal and childhood growth and development. On the basis of current knowledge, Levothyroxine Sodium, USP should therefore not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be treated.
Levothyroxine Sodium Nursing Considerations
Minimal amounts of thyroid hormones such as Levothyroxine Sodium are excreted in human milk. Thyroid hormones are not known to be associated with serious adverse effects and do not have known tumorigenic potential.
While caution should be exercised when Levothyroxine Sodium is administered to a nursing woman, adequate replacement doses of Thyronorm Tablets (Levothyroxine Sodium) are generally necessary to maintain normal lactation.